Mouse Bile salt export pump (ABCB11) ELISA Kit

ABCB11 is an ABC transporter named BSEP (Bile Salt Export Pump), or sPgp (sister of P-glycoprotein). This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily. Some members of the MDR/TAP subfamily are involved in multidrug resistance. This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver cells) to the bile. In humans, the activity of this transporter is the major determinant of bile formation and bile flow.

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SPECIFICATIONS

Catalog Number

KTE70528

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

27413

Accession

Q9QY30

Additional Info

Mouse Bile salt export pump (ABCB11) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ABCB11. No significant cross-reactivity or interference between Mouse ABCB11 and analogues was observed.