Mouse ATP-binding cassette sub-family G member 2 (ABCG2) ELISA Kit

ATP-binding cassette, sub-family G (WHITE), member 2 is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

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SPECIFICATIONS

Catalog Number

KTE70532

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

26357

Accession

Q7TMS5

Additional Info

Mouse ATP-binding cassette sub-family G member 2 (ABCG2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ABCG2. No significant cross-reactivity or interference between Mouse ABCG2 and analogues was observed.