Mouse Adenylate cyclase type 10 (ADCY10) ELISA Kit

Adenylate cyclase type 10 is a protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble in testis but particulate in sperm and other tissues. It is unlike other mammalian adenylyl cyclases because it is insensitive to G protein or forskolin regulation and is directly regulated by bicarbonate. It is localized in the cytoplasm and to organelles and is thought to function as a general bicarbonate sensor throughout the body. It plays an important role in the generation of cAMP in spermatozoa, playing possible roles in sperm capacitation, hypermotility, and/or the acrosome reaction.Genetic variations in this gene are associated with absorptive hypercalciuria type 2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

KTE70555

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

271639

Accession

Q8C0T9

Additional Info

Mouse Adenylate cyclase type 10 (ADCY10) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ADCY10. No significant cross-reactivity or interference between Mouse ADCY10 and analogues was observed.