Mouse Adenosine receptor A2a (ADORA2A) ELISA Kit

ADORA2a is a member of the G protein-coupled receptor (GPCR) family which possess seven transmembrane alpha helices. The crystallographic structure of the adenosine A2A receptor PDB 3EML (see figure to the right) reveals a ligand binding pocket distinct from that of other structurally determined GPCRs.\nAdenosine A2a Receptoris one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein-coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.As with the A1, the A2A receptors are believed to play a role in regulating myocardial oxygen consumption and coronary blood flow.

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SPECIFICATIONS

Catalog Number

KTE70562

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

11540

Accession

Q60613

Additional Info

Mouse Adenosine receptor A2a (ADORA2A) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ADORA2A. No significant cross-reactivity or interference between Mouse ADORA2A and analogues was observed.