Mouse Adenosine receptor A1 (ADORA1) ELISA Kit

The receptor is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.\nActivation of the adenosine A1 receptor by an agonist causes binding of Gi1/2/3 or Go protein. Binding of Gi1/2/3 causes an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration.

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SPECIFICATIONS

Catalog Number

KTE70561

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

11539

Accession

Q60612

Additional Info

Mouse Adenosine receptor A1 (ADORA1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ADORA1. No significant cross-reactivity or interference between Mouse ADORA1 and analogues was observed.