Mouse Activin receptor type-2B (ACVR2B) ELISA Kit

ACVR2B is an activin type 2 receptor. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity.\nType I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

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SPECIFICATIONS

Catalog Number

KTE70549

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

11481

Accession

P27040

Additional Info

Mouse Activin receptor type-2B (ACVR2B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ACVR2B. No significant cross-reactivity or interference between Mouse ACVR2B and analogues was observed.