Mouse 8-Hydroxy-desoxyguanosine (8-OHdG) ELISA Kit

8-oxo-7,8-dihydro-2 deoxyguanosine(8-OHdG), is probably the most important product of "oxidative stressвЂќ in DNA. Its concentration in DNA is, in fact. a quantitative analysis of the degree of DNA damage that an organism has undergone. Due to the importance of 8-OHdG of nucleic acidg in mutagenesis, carcinogenesis and aging, numerous chemical and biological investigations have been made on this subject in the past time. Kuchino and co-workers have found that 8-OHdG residue in DNA is misreading during the process of DNA replication. Recently, some reports have been presented on high 8-OHdG levels in patients suffering from various diseases such as chronic hepatitis, Fanconi s anemia, diabetes mellitus and Helicobacter pylori infections. As a result, 8-OHdG is a useful marker for the study of DNA damage arising from reactive oxygen species and is of great significance for cancer research.

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SPECIFICATIONS

Catalog Number

KTE70521

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Additional Info

Mouse 8-Hydroxy-desoxyguanosine (8-OHdG) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse 8-OHdG. No significant cross-reactivity or interference between Mouse 8-OHdG and analogues was observed.