Mouse 3-phosphoinositide-dependent protein kinase 1 (PDPK1) ELISA Kit

PDPK1 is a master kinase, which is crucial for the activation of AKT/PKB and many other AGC kinases including PKC, S6K, SGK. An important role for PDPK1 is in the signalling pathways activated by several growth factors and hormones including insulin signalling. Mice lacking PDPK1 die during early embryonic development, indicating that this enzyme is critical for transmitting the growth-promoting signals nescessary for normal mammalian development.\nMice that are deficient in PDPK1 have a ?40% decrease in body mass, mild glucose intolerance, and are resitant to cancer brought about by hyperactivation of the PI3K pathway (PTEN +/-).The structure of PDPK1 can be divided into two domains; the kinase or catalytic domain and the PH domain.

Prices direct from Abbkine Scientific Co.Ltd.

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

KTE70776

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18607

Accession

Q9Z2A0

Additional Info

Mouse 3-phosphoinositide-dependent protein kinase 1 (PDPK1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PDPK1. No significant cross-reactivity or interference between Mouse PDPK1 and analogues was observed.