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IL-1? Polyclonal Antibody

Cat no: ABP52932

IL-1? Polyclonal Antibody

Interleukin-1 beta encoded by IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

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SPECIFICATIONS

Catalog Number

ABP52932

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

3553

Isotype

Rabbit IgG

Accession

P01584

Clonality

Polyclonal

Concentration

1 mg/ml

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