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IGF-IR Polyclonal Antibody

Cat no: ABP51596

IGF-IR Polyclonal Antibody

Insulin-like growth factor 1 receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

ABP51596

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

3480/3643

Isotype

Rabbit IgG

Accession

P08069/P06213

Clonality

Polyclonal

Concentration

1 mg/ml

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