Human UDP-glucose ceramide glucosyltransferase (UGCG) ELISA Kit

Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase (UGCG) catalyzes the first glycosylation step in GSL biosynthesis.\nThe product, glucosylceramide, is the core structure of more than 300 GSLs. Ichikawa et al. cloned a UGCG cDNA by expressing a human melanoma cell cDNA library in a UGCG-deficient cell line and screening for UGCG complementation. The predicted 394-amino acid UGCG protein has a potential signal-anchor sequence and a single transmembrane domain near the N terminus, and very hydrophobic regions close to the C terminus, which may interact with the membrane.

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SPECIFICATIONS

Catalog Number

KTE62308

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

7357

Accession

Q16739

Additional Info

Human UDP-glucose ceramide glucosyltransferase (UGCG) ELISA Kit has high sensitivity and excellent specificity for detection of Human UGCG. No significant cross-reactivity or interference between Human UGCG and analogues was observed.