Human Transcription factor E2F1 (E2F1) ELISA Kit

E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner.

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SPECIFICATIONS

Catalog Number

KTE61962

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1869

Accession

Q01094

Additional Info

Human Transcription factor E2F1 (E2F1) ELISA Kit has high sensitivity and excellent specificity for detection of Human E2F1. No significant cross-reactivity or interference between Human E2F1 and analogues was observed.