Human Stem cell factor/mast cell growth factor (SCF/MGF) ELISA Kit

Stem cell factor (SCF;MGF) is a cytokine which binds CD117 (c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E(burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid). SCF, along with bFGF (basic fibroblast growth factor) and LIF (leukemia inhibitory factor), prevents spontaneous differentiation of primitive embryonic stem cells in cell culture.

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SPECIFICATIONS

Catalog Number

KTE61911

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4254

Accession

P21583

Additional Info

Human Stem cell factor/mast cell growth factor (SCF/MGF) ELISA Kit has high sensitivity and excellent specificity for detection of Human KITLG. No significant cross-reactivity or interference between Human KITLG and analogues was observed.