Human Ragulator complex protein LAMTOR3 (MAPKSP1) ELISA Kit

Mitogen-activated protein kinase scaffold protein 1 is an enzyme identified as an interacting protein that binds specifically to MAP kinase kinase MAP2K1/MEK1 and to MAP kinase MAPK2/ERK1. This protein enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade. When overexpressed in cultured cells, MP1 enhanced activation of ERK1 and activation of a reporter driven by the transcription factor ELK1. Expression of MP1 in cells increased binding of ERK1 to MEK1. MP1 apparently functions as an adaptor to enhance the efficiency of the MAP kinase cascade. The mTORC1 kinase promotes growth in response to growth factors, energy levels, and amino acids, and its activity is often deregulated in disease.

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SPECIFICATIONS

Catalog Number

KTE61726

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

8649

Accession

Q9UHA4

Additional Info

Human Ragulator complex protein LAMTOR3 (MAPKSP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human MAPKSP1. No significant cross-reactivity or interference between Human MAPKSP1 and analogues was observed.