Human Putative potassium channel regulatory protein (KCNRG) ELISA Kit

KCNRG is a soluble protein with characteristics suggesting it forms hetero-tetramers with voltage-gated K+ channels and inhibits their function. KCNRG has been found to be predominatly expressed in lung tissue. Additionally, KCNRG transcripts are also found in liver and some other tissues, but in lower extent. Researchers at Uppsala University have found that KCNRG is found in the lower lung and constitutes an autoantigen in a rare disorder named autoimmune polyendocrine syndrome type 1 (APS1). As a subset of patients with APS1 suffer from respiratory disease, an autoimmune reaction against KCNRG may explain the respiratory disease in these patients. KCNRG may also be connected to common nonfatal diseases like asthma and chronic bronchitis.

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SPECIFICATIONS

Catalog Number

KTE61927

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

283518

Accession

Q8N5I3

Additional Info

Human Putative potassium channel regulatory protein (KCNRG) ELISA Kit has high sensitivity and excellent specificity for detection of Human KCNRG. No significant cross-reactivity or interference between Human KCNRG and analogues was observed.