Human Perilipin-4 (KIAA1881) ELISA Kit

Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets The predicted 1,348-amino acid protein is homologous to the mouse plasma membrane-associated protein S3-12. RT-PCR ELISA detected ubiquitous expression of PLIN4, with highest expression in skeletal muscle, followed by heart and liver, and lowest expression in adult whole brain. Using immunofluorescence microscopy, Wolins et al. (2003) demonstrated that supplementation of mouse adipocytes with fatty acids resulted in a shift from diffuse S3-12 cytoplasmic expression to S3-12 coating of lipid droplets on the cell periphery. Over time, Plin1 coexpression was observed. Formation of S3-12-coated droplets required glucose and fatty acids that could be incorporated into triacylglycerol and was dependent on insulin.

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SPECIFICATIONS

Catalog Number

KTE61921

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

729359

Accession

Q96Q06

Additional Info

Human Perilipin-4 (KIAA1881) ELISA Kit has high sensitivity and excellent specificity for detection of Human KIAA1881. No significant cross-reactivity or interference between Human KIAA1881 and analogues was observed.