Human Nexilin (NEXN) ELISA Kit

The name nexilin came from the Latin word nexilis, meaning 'bound together.' Full-length b-nexilin contains an N-terminal F-actin-binding domain (ABD), followed by a spacer, a coiled-coil region, a second ABD, and a long C-terminal tail. In comparison, s-nexilin lacks the N-terminal ABD and has an insertion in the C-terminal tail. Immunofluorescence microscopy revealed that both b-nexilin and s-nexilin colocalized with F-actin at focal contacts at the ends of stress fibers.\nThe nexilins did not localize to cell-cell junctions. Western blot analysis detected nexilin proteins with apparent molecular masses above 90 kD in rat brain, testis, and spleen and in cultured rodent fibroblasts. Neither protein was detected in liver, kidney, or epithelial cell lines.

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SPECIFICATIONS

Catalog Number

KTE62219

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

91624

Accession

Q0ZGT2

Additional Info

Human Nexilin (NEXN) ELISA Kit has high sensitivity and excellent specificity for detection of Human NEXN. No significant cross-reactivity or interference between Human NEXN and analogues was observed.