Human Nephronectin (NPNT) ELISA Kit

Nephronectin contains 561 amino acids. In situ hybridization detected nephronectin in the developing mouse kidney and in several other tissues and organs. Expression appeared particularly prominent at epithelial-mesenchymal interfaces in tissues undergoing morphogenesis.\nThe deduced 565- and 582-amino acid proteins have calculated molecular masses of 61.9 and 64.0 kD, respectively. Both proteins contain an N-terminal signal sequence, followed by 5 EGF domains, and a C-terminal MAM domain. They also contain an RGD integrin-binding site, a potential glycosylation site, and a potential tyrosine phosphorylation site. EGF repeats 2, 4, and 5 contain Ca(2+)-binding EGF domains. In the longer variant, the 17 additional amino acids are inserted N-terminal to the first EGF domain.

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SPECIFICATIONS

Catalog Number

KTE62216

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

255743

Accession

Q6UXI9

Additional Info

Human Nephronectin (NPNT) ELISA Kit has high sensitivity and excellent specificity for detection of Human NPNT. No significant cross-reactivity or interference between Human NPNT and analogues was observed.