Human Nanos homolog 2 (NANOS2) ELISA Kit

NANOS2 (Nanos C2HC-Type Zinc Finger 2) is a Protein Coding gene. GO annotations related to this gene includeВ mRNA binding. An important paralog of this gene isВ NANOS3. Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state (By similarity).

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SPECIFICATIONS

Catalog Number

KTE61377

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

339345

Accession

P60321

Additional Info

Human Nanos homolog 2 (NANOS2) ELISA Kit has high sensitivity and excellent specificity for detection of Human NANOS2. No significant cross-reactivity or interference between Human NANOS2 and analogues was observed.