Human NADH-cytochrome b5 reductase 3 (CYB5R3) ELISA Kit

CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in CYB5R3 cause methemoglobinemias.

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SPECIFICATIONS

Catalog Number

KTE62186

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1727

Accession

P00387

Additional Info

Human NADH-cytochrome b5 reductase 3 (CYB5R3) ELISA Kit has high sensitivity and excellent specificity for detection of Human CYB5R3. No significant cross-reactivity or interference between Human CYB5R3 and analogues was observed.