Human Mucosae associated epithelia chemokine (MEC) ELISA Kit

CCL28 is a chemokine. CCL28 regulates the chemotaxis of cells that express the chemokine receptors CCR3 and CCR10. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3.\nThis chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. CCL28 has also been implicated in the migration of IgA-expressing cells to the mammary gland, salivary gland, intestine and other mucosal tissues.

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SPECIFICATIONS

Catalog Number

KTE62290

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

56477

Accession

Q9NRJ3

Additional Info

Human Mucosae associated epithelia chemokine (MEC) ELISA Kit has high sensitivity and excellent specificity for detection of Human CCL28. No significant cross-reactivity or interference between Human CCL28 and analogues was observed.