Human Microtubule-associated protein RP/EB family member 2 (MAPRE2) ELISA Kit

MAPRE2 shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.\nThe deduced 327-amino acid protein has significant homology with EB1 family proteins. Northern blot analysis detected a 2.6-kb transcript in T cells activated by 2 signals (i.e., cell surface antigen(s) and/or cytokine) and also in lymphocyte tumor cell lines. Immunoprecipitation analysis indicated that RP1 associates with full-length but not C terminus-deleted APC.

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SPECIFICATIONS

Catalog Number

KTE61724

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10982

Accession

Q15555

Additional Info

Human Microtubule-associated protein RP/EB family member 2 (MAPRE2) ELISA Kit has high sensitivity and excellent specificity for detection of Human MAPRE2. No significant cross-reactivity or interference between Human MAPRE2 and analogues was observed.