Human Meprin A subunit beta (MEP1B) ELISA Kit

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha (MEP1A) are secreted; oligomers containing meprin-beta are associated with the plasma membrane.\nMep1b- mice were born at half the expected mendelian ratio, but those that survived developed normally and were viable and fertile. Mutant mice lacked membrane-associated Mep1a in kidney and intestine, and microarray analysis indicated that renal gene expression profiles were different than those of wildtype mice.

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SPECIFICATIONS

Catalog Number

KTE62233

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4225

Accession

Q16820

Additional Info

Human Meprin A subunit beta (MEP1B) ELISA Kit has high sensitivity and excellent specificity for detection of Human MEP1B. No significant cross-reactivity or interference between Human MEP1B and analogues was observed.