Human MAP kinase-activated protein kinase 5 (MAPKAPK5) ELISA Kit

MAP kinase-activated protein kinase 5 is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.MAPKAPK5 encodes a predicted 471-amino acid protein that shares 20 to 30% sequence identity with RSK, MNK, and MAPKAPK kinases. MAPKAPK5 contains the conserved protein kinase domains I through XI, which are characteristic of all protein kinases.

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SPECIFICATIONS

Catalog Number

KTE61728

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

8550

Accession

Q8IW41

Additional Info

Human MAP kinase-activated protein kinase 5 (MAPKAPK5) ELISA Kit has high sensitivity and excellent specificity for detection of Human MAPKAPK5. No significant cross-reactivity or interference between Human MAPKAPK5 and analogues was observed.