Human MAP kinase-activated protein kinase 2 (MAPKAPK2) ELISA Kit

MAP kinase-activated protein kinase 2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation.\nHeat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.The cDNA sequence revealed the following features (in 5-prime to 3-prime order): a proline-rich region containing 2 putative SH3-binding sites, a kinase catalytic domain, a threonine residue phosphorylated by MAP kinase, and a nuclear localization signal.

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SPECIFICATIONS

Catalog Number

KTE61730

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

9261

Accession

P49137

Additional Info

Human MAP kinase-activated protein kinase 2 (MAPKAPK2) ELISA Kit has high sensitivity and excellent specificity for detection of Human MAPKAPK2. No significant cross-reactivity or interference between Human MAPKAPK2 and analogues was observed.