Human Low-density lipoprotein receptor-related protein 2 (LRP2) ELISA Kit

LRP2 is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins.

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SPECIFICATIONS

Catalog Number

KTE61783

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4036

Accession

P98164

Additional Info

Human Low-density lipoprotein receptor-related protein 2 (LRP2) ELISA Kit has high sensitivity and excellent specificity for detection of Human LRP2. No significant cross-reactivity or interference between Human LRP2 and analogues was observed.