Human Keratin, type I cytoskeletal 13 (KRT13) ELISA Kit

Keratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.\nThis type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.

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SPECIFICATIONS

Catalog Number

KTE61885

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

3860

Accession

P13646

Additional Info

Human Keratin, type I cytoskeletal 13 (KRT13) ELISA Kit has high sensitivity and excellent specificity for detection of Human KRT13. No significant cross-reactivity or interference between Human KRT13 and analogues was observed.