Human Kallikrein 8 (KLK8) ELISA Kit

Originally described from mouse brain, KLK8 was implicated in neural plasticity and learning. Kallikrein 8 is thought to be involved in neurite outgrowth and fasciculation during nervous system development. Kallikrein 8 is induced in neurite injury, and Kallikrein 8 has been shown to be elevated in the hippocampus on AlzheimerвЂ™s patients.\nKallikrein 8 is thought to regulate the early phase of long-term potentiation (LTP), possibly by cleaving fibronectin and other substrates.Kallikrein 8 is also found in the uterus, where it is hormonally regulated. Cervical cancer cell lines express high levels of Kallikrein 8, and it may be useful as a tumor marker. Kallikrein 8 is not limited to the brain and uterus, as many tissues and cell lines make the protein.

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SPECIFICATIONS

Catalog Number

KTE61893

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

11202

Accession

O60259

Additional Info

Human Kallikrein 8 (KLK8) ELISA Kit has high sensitivity and excellent specificity for detection of Human KLK8. No significant cross-reactivity or interference between Human KLK8 and analogues was observed.