Human Kallikrein 6 (KLK 6) ELISA Kit

Kallikrein 6, also known as Zyme, Neurosin, PRSS9, myelencephalon-specific protease (MSP) and protease M, is a trypsin-like serine proteinase. Kallikrein 6 was originally described from the brain as an enzyme involved in degradation of amyloid plaque protein (APP) and hK6 was thought to be a beta secretase.\nKallikrein 6 was shown to be elevated in the sera patients with AlzheimerвЂ™s disease and ParkinsonвЂ™s disease and in animal models of multiple sclerosis. The neuronal protein alpha-synuclein was shown to be cleaved by hK6, as has APP and hK6 has been implicated in vascular morphogenesis and angiogenesis. MSP has also been shown to rapidly degrade myelin-specific protein, laminin and fibronectin.

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SPECIFICATIONS

Catalog Number

KTE61895

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5653

Accession

Q92876

Additional Info

Human Kallikrein 6 (KLK 6) ELISA Kit has high sensitivity and excellent specificity for detection of Human KLK6. No significant cross-reactivity or interference between Human KLK6 and analogues was observed.