Human Kallikrein-5 (KLK5) ELISA Kit

KLK5 belongs to the kallikrein subgroup of serine proteases, which have diverse physiologic functions in many tissues. For background information on kallikreins.Using a positional candidate approach to identify additional KLK genes on 19q13.3-q13.4, followed by EST database searching and PCR, Yousef and Diamandis (1999) obtained a cDNA encoding KLK5, which they called KLKL2. RT-PCR analysis detected expression primarily in brain, mammary gland, and testis, with lower levels in other tissues.Kim et al. (2001) noted that KLK5 is expressed in a subset of ovarian tumors. They found a strong positive correlation between KLK5 expression and tumor grade and disease stage. They concluded that KLK5 expression is associated with more aggressive forms of epithelial ovarian carcinoma.

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SPECIFICATIONS

Catalog Number

KTE61896

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

25818

Accession

Q9Y337

Additional Info

Human Kallikrein-5 (KLK5) ELISA Kit has high sensitivity and excellent specificity for detection of Human KLK5. No significant cross-reactivity or interference between Human KLK5 and analogues was observed.