Human Kallikrein 10 (KLK10) ELISA Kit

KLK10 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.\nThe deduced 276-amino acid protein contains a putative signal peptide, followed by a short activating peptide and the protease domain, which includes the catalytic triad of his86, asp137, and ser229. KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined.

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SPECIFICATIONS

Catalog Number

KTE61902

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5655

Accession

O43240

Additional Info

Human Kallikrein 10 (KLK10) ELISA Kit has high sensitivity and excellent specificity for detection of Human KLK10. No significant cross-reactivity or interference between Human KLK10 and analogues was observed.