Human Interleukin-5 receptor subunit alpha (IL5RA/IL5R) ELISA Kit

The protein encoded by IL5RA is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

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SPECIFICATIONS

Catalog Number

KTE62205

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

3568

Accession

Q01344

Additional Info

Human Interleukin-5 receptor subunit alpha (IL5RA/IL5R) ELISA Kit has high sensitivity and excellent specificity for detection of Human IL5RA. No significant cross-reactivity or interference between Human IL5RA and analogues was observed.