Human Folate receptor beta (FOLR2) ELISA Kit

Folate receptor beta is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells.\nThis protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

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SPECIFICATIONS

Catalog Number

KTE62254

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

2350

Accession

P14207

Additional Info

Human Folate receptor beta (FOLR2) ELISA Kit has high sensitivity and excellent specificity for detection of Human FOLR2. No significant cross-reactivity or interference between Human FOLR2 and analogues was observed.