Human Factor-related Apoptosis (FAS) ELISA Kit

Fas is a glycoprotein with a mass estimated at 43 to 48 kDa . Fas is a member of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), and it shares a cytoplasmic motif with TNF RI, referred to as the death domain, that binds cytoplasm signaling molecules to trigger the cytoplasmic apoptotic signal . Fas is expressed to a large extent on activated T and B lymphocytes, and on malignant lymphoid cells. To a lesser extent, Fas is expressed on cells from liver, heart, kidney, ovaries, and on many other malignant cells. \nYan et al. (2005) noted that the TNFRSF6 gene contains 9 exons. They identified an antisense transcript SAF within the 12.1-kb intron 1 that is transcribed in the opposite direction as the TNFRSF6 gene.

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SPECIFICATIONS

Catalog Number

KTE62259

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

355

Accession

P25445

Additional Info

Human Factor-related Apoptosis (FAS) ELISA Kit has high sensitivity and excellent specificity for detection of Human FAS. No significant cross-reactivity or interference between Human FAS and analogues was observed.