Human Endothelin-converting enzyme 1 (ECE1) ELISA Kit

Endothelin converting enzyme 1, also known as ECE1, is a enzyme which in humans is encoded by the ECE1 gene.Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to biologically active peptides.\nSchmidt et al. (1994) purified a membrane-bound protease activity from bovine endothelial cells that specifically converts the inactive form to EDN1. The enzyme was cleaved with trypsin and peptide sequencing analysis confirmed it to be a zinc-chelating metalloprotease containing the typical HEXXH (HELTH) motif. RT-PCR and cDNA screens were used to isolate the complete cDNAs of the bovine and human enzymes.

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SPECIFICATIONS

Catalog Number

KTE61959

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1889

Accession

P42892

Additional Info

Human Endothelin-converting enzyme 1 (ECE1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ECE1. No significant cross-reactivity or interference between Human ECE1 and analogues was observed.