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Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit

Cat no: KTE61676

Supplier: Abbkine Scientific Co.Ltd.
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MDM2 encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for MDM2 on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Catalogue number: KTE61676
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q00987
Gene: 4193
Additional info: Human E3 ubiquitin-protein ligase Mdm2 (MDM2) ELISA Kit has high sensitivity and excellent specificity for detection of Human MDM2. No significant cross-reactivity or interference between Human MDM2 and analogues was observed.

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