Human Dual specificity protein kinase CLK1 (CLK1) ELISA Kit

DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 also has microtubule-polymerizing activity that is independent of its protein kinase activity. The KIAA0369 cDNA encodes a 740-amino acid peptide that shares 72.3% amino acid identity with doublecortin. The protein has a doublecortin domain, a serine/proline-rich domain, and a calmodulin-dependent kinase-like domain. The authors also identified 4 splice variants of KIAA0369. All splice variants were expressed predominantly in fetal brain, with transcript sizes ranging from 8.0 to 5.0 kb. Varying expression of all isoforms was also seen in all 15 regions of adult human brain examined, with greatest expression seen in cerebral cortex, occipital pole, frontal lobe, amygdala, and hippocampus.

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SPECIFICATIONS

Catalog Number

KTE62280

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1195

Accession

P49759

Additional Info

Human Dual specificity protein kinase CLK1 (CLK1) ELISA Kit has high sensitivity and excellent specificity for detection of Human CLK1. No significant cross-reactivity or interference between Human CLK1 and analogues was observed.