Human Dickkopf-like protein 1 (DKKL1) ELISA Kit

The deduced 242-amino acid SGY protein, which is 22% identical to DKK3 and 59% identical to the mouse Sgy sequence, possesses 2 potential N-glycosylation sites. Northern blot and in situ hybridization analysis revealed expression of a 1.0-kb Sgy transcript in adult mouse testis and day-11 and -15 embryos. Western blot analysis showed that SGY is secreted as a 40- to 50-kD protein; deglycosylation reduced the protein by 5 to 10 kD. Functional analysis determined that SGY does not block Xenopus Wnt8, Wnt3a, or Wnt2b induction of a secondary axis in frog embryos.\nScott (2000) mapped the SGY gene to chromosome 19 based on sequence similarity between the SGY sequence and the chromosome 19 clones LLNLR-254A7 and LLNLR-278H5 .

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SPECIFICATIONS

Catalog Number

KTE62037

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

27120

Accession

Q9UK85

Additional Info

Human Dickkopf-like protein 1 (DKKL1) ELISA Kit has high sensitivity and excellent specificity for detection of Human DKKL1. No significant cross-reactivity or interference between Human DKKL1 and analogues was observed.