Human Destrin (DSTN) ELISA Kit

Destrin belongs to the actin-binding proteins ADF/cofilin family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.\nIn a variety of eukaryotes, destrin regulates actin in the cytoskeleton. Destrin binds actin and is thought to connect it as gelsolin segment-1 does. Furthermore, the binding of actin by destrin and cofilin is regulated negatively by phosphorylation. Destrin can also sever actin filaments. At a pH of 7.3 or higher it can sever the filaments but a lower pH the ability for it to do so is limited.

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SPECIFICATIONS

Catalog Number

KTE62264

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

11034

Accession

P60981

Additional Info

Human Destrin (DSTN) ELISA Kit has high sensitivity and excellent specificity for detection of Human DSTN. No significant cross-reactivity or interference between Human DSTN and analogues was observed.