Human Desert hedgehog (DHH) ELISA Kit

DHH encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

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SPECIFICATIONS

Catalog Number

KTE62067

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

50846

Accession

O43323

Additional Info

Human Desert hedgehog (DHH) ELISA Kit has high sensitivity and excellent specificity for detection of Human DHH. No significant cross-reactivity or interference between Human DHH and analogues was observed.