Human DEP domain-containing protein 5 (DEPDC5) ELISA Kit

DEPDC5 encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by DEPDC5 is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in DEPDC5 are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of DEPDC5 has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

KTE62094

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

9681

Accession

O75140

Additional Info

Human DEP domain-containing protein 5 (DEPDC5) ELISA Kit has high sensitivity and excellent specificity for detection of Human DEPDC5. No significant cross-reactivity or interference between Human DEPDC5 and analogues was observed.