Human Delta (3,5)-Delta (2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) ELISA Kit

Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, ?3,5-?2,4-dienoyl-CoA isomerase, contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

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SPECIFICATIONS

Catalog Number

KTE61957

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1891

Accession

Q13011

Additional Info

Human Delta (3,5)-Delta (2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ECH1. No significant cross-reactivity or interference between Human ECH1 and analogues was observed.