Human Deleted In Liver Cancer 1 (DLC1) ELISA Kit

Deleted in Liver Cancer 1 is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers.DLC1 is frequently inactivated in human hepatocellular carcinoma, as well as some nasopharyngeal, lung, breast, prostate, kidney, colon, uterine, ovarian, and gastric cancers.\nThe DLC1 protein contains four major functional domains: an N-terminal sterile ? motif (SAM), a serine-rich (SR) region, a Rho-GAP domain, and a C-terminal steroidogenic acute regulatory protein related lipid-transfer (START) domain. DLC1 is localized to focal adhesions located at the periphery of cells.

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SPECIFICATIONS

Catalog Number

KTE62035

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

10395

Accession

Q96QB1

Additional Info

Human Deleted In Liver Cancer 1 (DLC1) ELISA Kit has high sensitivity and excellent specificity for detection of Human DLC1. No significant cross-reactivity or interference between Human DLC1 and analogues was observed.