Human Decorin/Bone proteoglycan II (DCN) ELISA Kit

DCN encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. DCN and the related gene biglycan are thought to be the result of a gene duplication. Mutations in DCN are associated with congenital stromal corneal dystrophy in human patients.

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SPECIFICATIONS

Catalog Number

KTE62128

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1634

Accession

P07585

Additional Info

Human Decorin/Bone proteoglycan II (DCN) ELISA Kit has high sensitivity and excellent specificity for detection of Human DCN. No significant cross-reactivity or interference between Human DCN and analogues was observed.