Human Cytoplasmic dynein 2 heavy chain 1 (DYNC2H1) ELISA Kit

DYNC2H1 encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins.\nThe light intermediate chains, with molecular masses of 55 to 59 kD, are unique to cytoplasmic dynein and contain consensus ATPase elements. Both axonemal and cytoplasmic dyneins also contain light chains of 8 to 25 kD.

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SPECIFICATIONS

Catalog Number

KTE61964

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

79659

Accession

Q8NCM8

Additional Info

Human Cytoplasmic dynein 2 heavy chain 1 (DYNC2H1) ELISA Kit has high sensitivity and excellent specificity for detection of Human DYNC2H1. No significant cross-reactivity or interference between Human DYNC2H1 and analogues was observed.