Human CD40 receptor/soluble (CD40) ELISA Kit

CD40 is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. In total CD40L has three binding partners: CD40, ?5?1 integrin and ?IIb?3.\nCD40L is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper IgM syndrome.

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SPECIFICATIONS

Catalog Number

KTE62285

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

958

Accession

P25942

Additional Info

Human CD40 receptor/soluble (CD40) ELISA Kit has high sensitivity and excellent specificity for detection of Human CD40. No significant cross-reactivity or interference between Human CD40 and analogues was observed.