Human Carboxypeptidase N catalytic chain (CPN1) ELISA Kit

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator.\nThis enzyme is a tetramer composed of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.The predicted protein is 458 amino acids long. Carboxypeptidase N is a 280-kD tetrameric complex consisting of 2 identical 83-kD regulatory subunits and 2 identical 50-kD catalytic subunits.

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SPECIFICATIONS

Catalog Number

KTE62274

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1369

Accession

P15169

Additional Info

Human Carboxypeptidase N catalytic chain (CPN1) ELISA Kit has high sensitivity and excellent specificity for detection of Human CPN1. No significant cross-reactivity or interference between Human CPN1 and analogues was observed.