Human Bcl-2-related protein A1 (BCL2A1) ELISA Kit

BCL2A1encodes a member of the bcl2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

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SPECIFICATIONS

Catalog Number

KTE62298

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

597

Accession

Q16548

Additional Info

Human Bcl-2-related protein A1 (BCL2A1) ELISA Kit has high sensitivity and excellent specificity for detection of Human BCL2A1. No significant cross-reactivity or interference between Human BCL2A1 and analogues was observed.