Human Apolipoprotein L1 (APOL1) ELISA Kit

Apolipoprotein L (APOL) proteins belong to the high density lipoprotein family, which plays a central role in cholesterol transport. The cholesterol content of membranes is important in cellular processes such as modulating gene transcription and signal transduction both in the adult brain and during neurodevelopment. The 6 APOL genes are clustered on chromosome 22q12.3.\nThe cDNA encodes a 383-amino acid polypeptide that includes a 12-amino acid secretory signal peptide. Northern blot analysis detected a 1.3-kb APOL transcript in the pancreas but not in any other human tissues. Affinity immunosorption showed that APOL is not free in the plasma, but is associated with lipoproteins containing APOA1. APOL was found in high density lipoprotein fractions.

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SPECIFICATIONS

Catalog Number

KTE62301

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

8542

Accession

O14791

Additional Info

Human Apolipoprotein L1 (APOL1) ELISA Kit has high sensitivity and excellent specificity for detection of Human APOL1. No significant cross-reactivity or interference between Human APOL1 and analogues was observed.