Human Alanyl (membrane) aminopeptidase (ANPEP) ELISA Kit

Alanine aminopeptidase (EC 3.4.11.2) is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is found at high levels in the urine when there are kidney problems.Also called AAP. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily.

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SPECIFICATIONS

Catalog Number

KTE62303

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

290

Accession

P15144

Additional Info

Human Alanyl (membrane) aminopeptidase (ANPEP) ELISA Kit has high sensitivity and excellent specificity for detection of Human ANPEP. No significant cross-reactivity or interference between Human ANPEP and analogues was observed.